Synthesis and antimicrobial activity evaluation of some benzimidazole and indole derivatives
نویسندگان
چکیده
منابع مشابه
Synthesis Antimicrobial Activity and Chemotherapeutic Potential some Novel Benzimidazole Derivatives
Benzimidazole derivates play vital role in biological field such as antimicrobial, antiviral, antidiabetic, and anticancer activity. Therapeutic significance of these clinically useful drugs in treatment of microbial infections encouraged the development of some more potent and significant compounds. With the purpose of finding new chemical entities with enhanced antimicrobial activity, a serie...
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Some new 3-[(5-benzylidene-2-phenyl)-3, 5-dihydro-4-H-imidazol-4-one-3-(4-bezoylhydrazono)]-indole-2-ones (VIII) have been synthesized from different isatinhydrazones (II) by condensing with 2-phenyl-5-benzylidene- 3-N (4-acetyl phenyl)-1, 5-dihydro-imidazol-4-one (VII). Their chemical structures have been confirmed by IR, 1HNMR, MASS and by elemental analysis. Investigation of antimicrobial ac...
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Synthesis and antimicrobial activities of some new benzimidazole derivatives.
Some benzimidazolylbenzamides were synthesized and their antimicrobial activities against Staphylococcus aureus, Streptococcus faecalis, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa and Candida albicans evaluated. It was shown that the compound 14 exhibited the best activity against B. subtilis, P. aeruginosa and C. albicans.
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ژورنال
عنوان ژورنال: African Journal of Microbiology Research
سال: 2013
ISSN: 1996-0808
DOI: 10.5897/ajmr12.1321